News

2024

Winter School XAI 2025: Registration Now Open!

At the beginning of the new year, the Winter School XAI 2025 will occur from January 6 to 10, 2025, at the Masaryk Oncology Institute in Brno and the Medical University of Graz. This unique program will provide practical insights into the latest artificial intelligence (AI) advancements in digital pathology.

Participants will engage in training sessions led by experts, covering essential topics such as AI-assisted diagnostics, the significance of explainability in medical AI, and certification processes according to the In Vitro Diagnostic Regulation (IVDR). The program also includes a practical component, allowing participants to work directly with digital pathology data, including whole-slide images and clinical data.

The education will be conducted by prominent professionals in the field who will share valuable insights into the future of AI in pathology. Participants in this school will deepen their knowledge and skills in digital pathology, data preparation for AI, and critical aspects of privacy protection.

Registration is open until December 15, 2024. To secure your place, please fill out the registration form. Take advantage of this opportunity to expand your knowledge!

 

 

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BioMedAI Team Showcases Research at the first ASDP Congress in Seoul

Representatives of the BIoMedAI project participated in the 1st Annual Congress of the Asian Society of Digital Pathology (ASDP), which took place from October 2 to 4, 2024, in Seoul, South Korea.

The delegation included Vít Musil, the team leader from the RationAI lab and Assistant professor at the Department of Computer Science, along with PhD student Adam Bajger and master's student Adam Kukučka, who presented the results of his research. This research, initially part of his bachelor’s thesis, is now under review.

The ASDP 2024 congress focused on the current status and guidelines for Asia's digital pathology (DP) and artificial intelligence (AI). It brought together experts from academia and industry to discuss how these technologies can be standardized and ethically applied to advance healthcare across the region. The program included sessions on the practical application of AI in pathology, emerging regulatory issues, and the latest innovations in digital pathology imaging. The conference provided a unique opportunity for attendees to network and exchange knowledge with global leaders in the field, further bridging the gap between research and real-world applications.

“Being allowed to attend the ASDP congress was a great honor and a life-changing experience. What impressed me most was the participants' passion for their work, making their presentations insightful and educational. Although I was nervous about presenting our project, I saw it as a valuable opportunity to learn something new and showcase part of what we’re working on at RationAI.”

Aleš Kukučka, master's student at FI MUNI

This conference was a valuable platform for connecting experts from pathology, informatics, academia, and business sectors, enabling a comprehensive view of the latest research and practical applications in digital pathology and AI.

 

 

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XAI Summer School 2024 Brings Together Experts and Enthusiasts in Brno

From September 2 to 6, 2024, the Faculty of Informatics and the Institute of Computer Science at Masaryk University in Brno hosted a successful summer school focused on Explainable Artificial Intelligence (XAI) in digital pathology. Organized by members of the BioMedAI project, the event attracted nearly 40 participants eager to explore the applications of AI in medicine.

Petr Holub from Masaryk University, one of the main organizers of the summer school and Project Lead of the BioMedAI project, shared his assessment of the event: "The atmosphere was incredibly positive, with students showing great enthusiasm and actively participating in all sessions. We managed to create a collaborative environment where participants could openly share their experiences and knowledge. The summer school's greatest achievement was providing practical skills in using XAI tools in digital pathology, which is crucial for many of the attendees’ research. The hands-on workshops, where participants could apply new methods and tools to real-world data, were particularly well-received and sparked the most interest."

Throughout the week, attendees engaged in lectures and hands-on exercises led by experts in the field, including Norman Zerbe from Charité, Heimo Müller from the Medical University of Graz, Aray Karjauv from Technical University Berlin, Tomáš Brázdil, Petr Holub and Vít Musil from Masaryk University, and Rudolf Nenutil from the Masaryk Memorial Cancer Institute. An online lecture on the state of the art of XAI in digital pathology was presented by David Steiner from Google. The program covered a wide range of topics, from the basics of pathology to advanced AI research, data management, and practical training using tools like RatioPath and RatioViz.

“The hands-on exercises and lectures by leading experts provided valuable insights into the applications of AI in digital pathology, which will definitely benefit my ongoing research.”

Aleksandra Zec, PhD student from Politecnico di Milano

Aleksandra Zec, a PhD student from Politecnico di Milano who is working with digital pathology data in her research, shared her positive experience: "I had a great time in Brno, especially since I am working with digital pathology data in my PhD research. Even though I’m quite familiar with the topic, I found the sessions to be both useful and comprehensive. The hands-on exercises and lectures by leading experts provided valuable insights into the applications of AI in digital pathology, which will definitely benefit my ongoing research."

The summer school provided participants with valuable practical experience and a deep understanding of the latest technologies in XAI. The event fostered a collaborative learning environment, inspiring attendees to actively engage with the future of medical innovation and contribute to the advancement of AI in medicine.

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“The atmosphere was incredibly positive, with students showing great enthusiasm and actively participating in all sessions.”

Petr Holub from Masaryk University, one of the main organizers

Successful Start of the XAI Summer School 2024

September 4, 2024

The XAI Summer School has successfully started, with nearly 40 participants attending lectures by experts in the field. Renowned speakers are sharing valuable insights and inspiring the next generation to explore this high-potential area that promises significant advancements in medicine.

The event fosters a collaborative learning environment, motivating participants to engage deeply with the future of medical innovation.

Program

Monday
10:00-10:15 Intro (Petr Holub)
10:15-12:15 Introduction to pathology (Rudolf Nenutil)
12:15-13:15 Lunch break
13:15-15:15 Intro to XAI on (not only digital pathology) imaging (Aray Karjauv)
15:15-15:30 Break
15:30-17:00 State of the art in (X)AI in digital pathology (Dave Steiner)

Tuesday
9:00-11:00 Data in digital pathology - images, annotations, metadata, clinical data. Clinical AI applications. (Norman Zerbe)
11:00-12:00 Handling sensitive data (Petr Holub)
12:00-13:00 Lunch break
13:00-13:20 Metacentrum Registration (Vít Musil)
13:20-14:20 Handling data quality (Karel Štěpka)
14:20-14:30 Break
14:30-16:30 Mining clinical data (Aleš Horák)

Wednesday
9:00-12:00 Hands-on: Training a simple AI model in digital pathology (part 1) (Vít Musil)
12:00-13:00 Lunch break
13:00-15:30 Hands-on: Training a simple AI model in digital pathology (part 2) (Vít Musil)
15:30-16:00 Break
16:00-17:30 XAI in digital pathology (Aray Karjauv)

Thursday
9:00-10:30 Hands-on: Explainability of the trained model from Wednesday (Vít Musil)
10:30-11:00 Break
11:00-12:00 Clinical data relevant for pathology (Rudolf Nenutil)
12:00-13:00 Lunch break
13:00-16:00 Hands-on: Training AI model on Whole Slide images (part 1) (Vít Musil)

Friday
9:00-10:30 Hands-on: Model inference on WSI (Vít Musil)
10:30-12:00 Hands-on: Explainability (Vít Musil)
12:00-13:00 Lunch break
13:00-13:30 Wrap up of the school (Petr Holub)

 

 

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Peter Holub is a representative of the EOSC Association Health Data Task Force

August 15, 2024

The EOSC Association Task Forces play a key role in the development of the European Open Science Cloud (EOSC). These teams, composed of experts and volunteers from across Europe, focus on specific areas essential for the implementation and advancement of EOSC.

The recent reorganisation for the 2024–2025 period has brought significant changes. Peter Holub has been appointed as the Co-Chair of the Health Data Task Force, which has been operating in its new form since July this year. He will be directly involved in addressing issues related to the interoperability and use of health data in research, in accordance with FAIR principles.

"Medical data is the subject of numerous activities aimed at standardising it (e.g., ISO, HL7, and other standardisation bodies) and making it discoverable and accessible. My goal is to find ways in which EOSC can effectively support the use of medical data in scientific research. Access to medical data is one of the essential conditions for training AI models that advance medicine and improve treatment outcomes. This is also our focus at BioMedAI, where we use AI in oncopathology."

 

 

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XAI Winter School 2025

Dates: January 6-10, 2025
Place: the Masaryk Memorial Cancer Institute in Brno, Czech republic & the Medical University of Graz, Austria


From January 6 to 10, 2025, the Masaryk Memorial Cancer Institute in Brno and the Medical University of Graz will host a Winter School focused on Artificial Intelligence (AI) in digital pathology. This specialized program offers participants a hands-on introduction to the latest advancements in AI, with a particular focus on its application in digital pathology.

Expert-led training on AI and Digital Pathology

Throughout the week, participants will attend lectures and practical sessions led by prominent experts in the field. These sessions will cover various topics, including the role of AI in assisting diagnoses, the importance of explainability in medical AI systems, and the certification processes required under the In Vitro Diagnostic Regulation (IVDR). Participants will also gain insight into preparing data for AI training, such as whole-slide images (WSIs), annotations, clinical and omics data, and data privacy considerations.

Hands-on experience in Brno and Graz

The program includes practical, hands-on sessions allowing participants to work directly with digital pathology data. Participants will practice scanning and saving WSIs, creating annotations, and extracting structured data from unstructured clinical data using advanced AI tools such as Natural Language Processing (NLP) and large language models (LLMs). The week will conclude with a tour of the state-of-the-art digital pathology infrastructure at the Medical University of Graz.

What Will Participants Gain from the Winter School?

  • Getting pathologists familiar with state-of-the-art in digital pathology
    ( Hands-on in Graz on entire digital pathology dept. )

  • Getting pathologists familiar with the possibilities of different AI approaches - from assistance to diagnosis

  • Getting familiar with explainability

  • Getting familiar with IVDR & certification processes

  • Training pathologists on how to prepare data for AI
    WSIs - formats
    WSI annotations - formats, semantics, SOPs
    clinical data - extraction manual vs. NLP vs. LLMs
    omics data - basic formats

  • Data privacy aspects - pseudonymized vs. anonymized data, types of contracts

Organizational aspects

1. Part - BRNO
The first part of the Winter School will take place from January 6 to 8, 2025, at the Masaryk Memorial Cancer Institute in Brno, where participants will focus on introductory sessions, AI use in digital pathology, and practical hands-on training.

>>> Transfer to Medical University Graz by train on Wednesday evening

2. part - GRAZ
On the evening of January 8, participants will travel by train to Medical University Graz, where the second part of the program will be held from January 9 to 10, 2025. In Graz, participants will experience a guided tour of the digital pathology infrastructure and gain additional practical insights.

Registration information

Registration takes place via the form. You can register until 15 December. After that time, registration will be closed.
The registered participants will receive an informative email regarding the organization and other details of the school at the latest by 20 December 2024.


Fees

Participation is free of charge.
Participants are expected to cover their travel and accommodation expenses.

Bridging Medicine and Technology: The BioMedAI Project Sheds Light on Cancer Diagnosis with AI

16. 4. 2024

The non-profit organization Science Party hosted an event spotlighting the collaborative efforts of pathologists and IT specialists from the BioMedAI project as they presented the challenge of cancer using AI!

Through the BioMedAI project, they demonstrated to the public how they're reshaping medicine and computer science. Their efforts in training AI to identify prostate cancer cells are speeding the diagnosis and treatment of the disease and setting a new standard in interdisciplinary collaboration.

Pathologist Rudolf Nenutil from the Masaryk Cancer Memorial Institute captivated everyone by comparing studying cells to detective work. At the same time, IT scientist Tomáš Brázdil explained the complexities of training AI to the audience.

This lecture wasn't just for specialists - it was a gathering for the wider community, showcasing the incredible strides in the fight against cancer through the power of AI.

Event: https://www.scienceparty.cz/udalost/24_02

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Photo: Lucie Skřičková, Masaryk University

Rudolf Nenutil on the program BILANCE featured by Czech Television

6. 3. 2024

BILANCE is a journalistic format focusing on the analysis and evaluation of current events and topics in Czech society. The March edition of the program tackled the theme "Will We Beat Cancer?" and brought many updates from the field of cancer diagnostics and treatment.

Rudolf Nenutil, a medical oncopathologist, introduced software utilizing artificial intelligence for the recognition of cancerous findings. He collaborates with a team of computer scientists from Masaryk University on the BioMedAI project, which holds revolutionary potential in the field of cancer diagnostics.

To watch the program in the Czech language: BILANCE - Porazíme rakovinu? 

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Photo: MOÚ
Source: www.mou.cz

Pathologist Rudolf Nenutil featured on Czech Radio podcast: Discussion on Software Development utilizing artificial intelligence for cancer detection

7. 2. 2024

Pathologist Rudolf Nenutil recently appeared as a guest on a popular Czech Radio podcast, where he shared insights into the development of software utilizing artificial intelligence for the detection of cancerous findings. Collaborating with a team of computer scientists from Masaryk University, he contributes to the BioMedAI project, which holds revolutionary potential in the field of cancer diagnostics.

During the interview, Nenutil emphasized that traditional methods of pathological examination of tissue under a microscope have seen little advancement over the past one hundred and twenty years. However, the new software has the potential to significantly increase the efficiency and accuracy of diagnostics, enabling faster and more precise identification of tumors. The software can capture even the smallest changes that might escape the attention of pathologists.

Additionally, the podcast delves into the importance of pathologists' work, which plays a crucial role in the cancer treatment process, and the significance of the new software, which could greatly facilitate and improve the entire treatment process.

You can listen to the whole interview in the Czech language: Metoda rozpoznávání rakovinových nálezů se 120 let nezměnila. Práci pomůže zrychlit nový software | Brno (rozhlas.cz)

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Author: Ludmila Opltová from The Czech Radio BRNO

Petr Holub, BioMedAI representative, contributes to discussion on FAIR data and the impact of AI on research  

24.–24. 1. 2024

In late January, a discussion regarding the significance of integrating FAIR data into scientific research occurred in Milan. The event ESFRI-EOSC Policy Workshop on "FAIR Data Productivity and Advanced Digitalization" brought together representatives from European research infrastructures to delve into the future of research.

Petr Holub, representing BioMedAi and BBMRI, actively participated in this discussion and highlighted the indispensable role of artificial intelligence in medical research. Specifically, he emphasized its significance in digital pathology for cancer diagnosis and treatment and pointed out its contribution to anonymizing and synthesizing data for publication, addressing the ongoing challenge of managing sensitive data. Holub's speech underscored that the role of EOSC extends beyond mere funding; it plays a crucial part in facilitating these essential tasks.

Experts also emphasized the importance of collaboration within research communities to ensure effective implementation of FAIR data practices and discussed challenges including staff training, data accessibility, and management of sensitive data.

Czech Open Source Policy Forum Highlights Contributions from BioMedAI

On April 24, 2024, the Czech Open Source Policy Forum took place in Brno, featuring prominent discussions on the sustainability of open-source projects within the public sector and academia. Among the attendees was Petr Holub, a representative from the BioMedAI project. He actively participated in discussions focused on the importance of community engagement for the sustainability of these initiatives. Holub's insights contributed to a deeper understanding of how collaborative efforts can enhance the longevity and impact of open-source projects.

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2023

Petr Holub Explores AI's Role in Cancer Care at Brno Oncology Days

1.–3. 11. 2023 - Brno Oncology Days, Brno

IT specialist Petr Holub, the project lead of the BioMedAI project, delivered a lecture at the prestigious professional symposium, Brno Oncology Days 2023, focusing on the latest insights and practices in the field of oncology. His presentation into the utilization of advanced technologies in the diagnosis and treatment of cancer. Petr Holub concentrated on the potential of artificial intelligence and data analysis, emphasizing their significant contribution to personalized medicine and the streamlining of clinical studies.

Participants at the Brno Oncology Days symposium had a unique opportunity to hear from Petr Holub, recognized as one of the leading experts in IT applications in medicine and a key figure in the BioMedAI project. He underscored the importance of data security and protection in oncological research and practice. He also discussed the challenges posed by the integration of new technologies into existing healthcare systems and how these innovations can aid cancer patients.

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Integrating AI in Biomedicine: Highlights from the Czech Pathologists' Congress

26.–28. 10. 2023

The 48th Congress of Czech Pathologists taking place in Zlín, Czech Republic, featured a compelling showcase of the intersection between medical expertise and information technology, with a focus on the BioMedAI project. Key speakers IT specialist Tomáš Brázdil from Masaryk University and pathologist Rudolf Nenutil from Masaryk Memorial Cancer Institute collaborated to apply machine learning to pathology, aiming to enhance diagnostic accuracy through AI systems assisting pathologists in their work. Brázdil emphasized the significance of problem formulation, meticulous data preparation, and rigorous testing supervised by pathologists to ensure the effectiveness of AI systems in clinical practice. He provided a comprehensive overview of the entire process, emphasizing the need for collaboration between IT specialists and medical professionals. Nenutil's exploration of how neural networks can identify suspicious areas in prostate biopsies showcased the alignment of AI diagnostic features with traditional pathology techniques. He discussed the strengths and limitations of neural networks in pathology, advocating for ongoing research and development.

The presentations underscored the transformative potential of machine learning in enhancing medical diagnostics, positioning the BioMedAI project as a significant stride toward integrating AI in clinical settings. The congress highlighted the importance of a multidisciplinary approach for advancing contemporary medicine. The discussions and insights from Brázdil and Nenutil not only showcased progress in biomedicine but also emphasized the collaborative spirit driving innovation in healthcare.

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Project BioMedAI at the event AI 4 All: The Key to the Future

14. 10. at the Jiří Mahen Library, Brno

The AI 4 All event, held in Brno, Czech Republic, on October 14, 2023, in collaboration with the Jiří Mahen Library, engaged a diverse audience across age groups to explore the world of artificial intelligence. The program featured various lectures and workshops for adults, children, and students, providing practical demonstrations of AI applications in different fields, interactive quizzes, and creative workshops for the youngest participants. IT specalist Tomáš Brázdil from the Faculty of Informatics at Masaryk University contributed with a lecture on digital pathology, introducing an innovative assistance system based on machine learning with the potential to revolutionize diagnostic processes in medicine.

During his presentation, he emphasized his active participants on the BioMedAI project, which focuses on advanced artificial intelligence technologies for developing the new cancer treatment methods. His discourse underscored how AI can contribute to more precise and efficient diagnostics. The AI 4 All event provided an inspiring platform for experts and the public to meet, deepening awareness of the importance of AI in both current and future societies.

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Scientist Tomáš Brázdil unlocks AI secrets at event AI 4 Talents 

13. 10. at VIDA! Science Centre, Brno

As part of the AI 4 Talents event in the VIDA! Science Centre, Brno, Czech Republic, which attracted enthusiastic high school students and their educators, IT specalist Tomáš Brázdil from the Department of Machine Learning and Data Processing at the Faculty of Informatics, Masaryk University, made a significant presentation. His lecture titled "Neural Networks and Image Recognition: A Historical Journey with Surprises" provided attendees with a captivating insight into the development of neural networks and their applications, generating considerable interest among young talents.

Brázdil also shared information about the BioMedAI project, which is an example of applying artificial intelligence in medicine. Within this project, advanced AI technologies are utilized to develop new methods for cancer treatment, representing significant potential for improving healthcare and offering new hope for patients. His contribution thus demonstrated how artificial intelligence can positively impact not only the technological realm but also make a substantial contribution to the fields of biomedicine and healthcare.

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Petr Holub presented BioMedAI's role in advancing explainable AI     in medicine at BioTechX Europe 2023

4.–6. 10. 2023

At the BioTechX Europe conference, Petr Holub from BioMedAI took the stage to present groundbreaking advancements in the application of explainable artificial intelligence in medicine.

Holub's presentation at BioTechX Europe focused on the use of explainable AI in medicine, particularly in diagnosing prostate cancer. He emphasized how explaining AI models can boost their credibility in healthcare. Additionally, he highlighted BBMRI's vital role in providing samples and expertise, showcasing its significance in advancing explainable AI. The presentation showcased the potential of explainable AI in medical diagnosis and BioMedAI's dedication to healthcare innovation.

BioTechX Europe congress
Europe's largest congress focused on diagnostics, precision medicine, and digital transformation in pharmaceutical development and healthcare, gathering 3000 leaders, 400 speakers, and 100 start-ups. The last annual event was held in Basel in early October 2023.

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BioMedAI Workshop Graz

17.–19. 7. 2023

The July workshop focused on tissue sample preparation, scanning, and analysis. The networking workshop provided an overview of research topics, methods, and approaches to how different groups work and interact with medical environments. The participants also discussed the future of the project, e.g., educational events and summer schools within the BioMedAI project.

The event was attended by IT specialists from Masaryk University RationAI, Medical University Graz, and pathologists from Masaryk Memorial Cancer Institute.

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BioMedAI Project Takes Centre Stage on Czech TV's 'About Science and Scientists'

24. 6. 2023

In the Czech Television program "About Science and Scientists", aired on June 24, 2023, the spotlight was on the BioMedAI project. This pioneering project strives to harness the power of advanced artificial intelligence and machine learning methods within biomedical research and oncology. The show offered viewers an inside look at the collaborative efforts of scientists and IT specialists working together to develop algorithms that can analyze complex medical data and contribute to improved diagnostics and personalized cancer treatment.

The broadcast featured various aspects of the BioMedAI project, including its advantages for clinical practice and its potential impact on patients. The discussion highlighted the critical role of interdisciplinary cooperation between medicine and information technology, showcasing how cutting-edge technologies are forging new pathways in the battle against cancer. The program also paid close attention to the ethical considerations surrounding personal data and the confidentiality of information, underscoring their significance in this domain.

To watch the program in the Czech language: O vědě a vědcích: Umělá inteligence v onkologii

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Workshop on Introducing AI Groups

30.–31. 3. 2023

This workshop was a continuation of the XAI workshop earlier in the same week, which allowed individual AI groups contributing to the project to introduce to each other. This included groups from Masaryk university - RationAI, CBIA, VisitLab, NLPlab, and a group of prof. Novacek, a Group of dr. Müller from Medical University Graz, and DAIlabor from the Technical University Berlin. The networking workshop provided an overview of research topics, methods how different groups work and interact with the medical environments, and how the whole team can collaborate on preparation of educational events within the BioMedAI project.

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Workshop in Explainable AI Models

27.–29. 3. 2023

Explainability of AI models is helpful to support adoption of AI tools in medical environments and also means for AI developers to understand their models and steer their developments. The workshop focused on concepts of explainability and how explainability is applied to AI in digital pathology. The workshop participants prepared an extensive literature survey to provide a basis for the subsequent discussions. The main workshop topics included:

  • concepts of explainability and their use in AI models
  • explainability by design vs. post hoc explainability methods
  • explainability specifically in image analyses
  • certification of AI models in medicine and use of explainability for certification purposes
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Workshop on Infrastructures for Application of AI on Sensitive Data

8.–10. 3. 2023

Processing imaging data in whole slide images (WSI) is a major challenge for IA researchers - finding capacities to store and process the WSI while complying with the security requirements by the data sources. This workshop focused on getting an overview of SensitiveCloud service by CERIT-SC and how to use it not only for local processing at Masaryk University, but also by researchers at Medical University Graz and Technical University Berlin. The main topics included:

  • porting AI application to Kubernetes
  • running long-term services in SensitiveCloud
  • scaling up computations in SensitiveCloud
  • effective transfers of data from Graz to Brno
  • onboarding users from MMCI, MUG, and TUB
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Data Management Workshop

1.–3. 2. 2023

Management of large volumes of imaging, associated phenotypical/clinical and other data is becoming a challenge for health care institutions. We have organized a first in the series of workshops within the BioMedAI, focusing on bringing together experts on medical data management from Medical University Graz and Masaryk Memorial Cancer Institute with experts from Institute of Computer Science at Masaryk University focusing on building storage and data processing capacities as a part of national eInfrastructures.

The workshop allowed introducing medical partners of the project and dealt with the following topics:

  • what should be data formats for long-term storage of whole slide images?
  • what are the existing data flows and what should be a data flows in AI-assisted environments from pathologist perspective?
  • what are the state-of-the-art infrastructures for storing and processing sensitive data?

The partners introduced their existing solutions and gaps have been identified and discussed.

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